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Is there a limit on the number of separate prescriptions per schedule II substance that may be issued during the 90-day time period? The combined effect of these multiple prescriptions is to allow the patient to receive, over time, up to a 90-day supply of that controlled substance. Requirements for issuance: - Each prescription issued is for a legitimate medical purpose by an individual practitioner acting in the usual course of his/her professional practice.

How is the issuance of multiple schedule II prescriptions different than issuing a refill of a schedule II prescription? - The individual practitioner must provide written instructions on each prescription indicating the earliest date on which a pharmacy may fill each prescription - The issuance of multiple prescriptions is permissible under applicable state laws.

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